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Technical Documentation

Chemical analysis: Raman spectroscopy

Principle : The Raman spectroscopy is the inelastic scattering of light by molecules, that is to say, the broadcast involving the exchange of energy light-material.

The analysis is done by excitation of the material. raised to an energy level virtual by a powerful light source to be monochromatic type laser, it reémet then a write-off which is collected and then analyzed by a detector to be adequate. this radiation consists of two types of signals. the very first of the majority corresponds to the rayleigh scattering : the incident radiation is scattered elastically with no change of energy and therefore wavelength. however, photons in a very limited number of cases can interact with matter. it absorbs ( or transfers ) of energy to the photons, thereby producing the radiation, the stokes (anti-stokes). the energy variation observed at the photon provides information on the energy levels of rotation and vibration of the molecule concerned.

Interest/Objective:

It is often used for:

  • to identify organic molecules, polymers, biomolecules, and inorganic compounds both in overall densities (bulk and in individual particles
  • the imaging and depth profiling analysis, raman used to map the distribution of components in mixtures, such as drugs in excipients, tablets, and coatings for the absorption of the deferred drugs
  • determine the presence of different types of carbon (diamond, graphite, amorphous carbon, carbon adamantine, nanotubes) and their relative proportions, something for which it is particularly suited
  • determine inorganic oxides and their valence state
  • to measure the stress and crystalline structure in semiconductor and other materials

Liquid chromatography

Chemical analysis
6

Photoelectron microscopy

Chemical analysis
7

Size-exclusion chromatography

Chemical analysis
4

Mass spectrometry

Chemical analysis
7

Absorbance spectrophotometer and atomic emission

Chemical analysis
4

Gas chromatography

Chemical analysis
4

Raman spectroscopy

Chemical analysis
7

Mass spectroscopy of secondary ions

Chemical analysis
5
  • Chemical analysis: Raman spectroscopy
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